Stimulating Plants

Stimulant: Definition

1. something that temporarily quickens some vital process or the functional activity of some organ or part: Adrenalin is a stimulant for the heart.

2. any food or beverage that stimulates, esp. coffee, tea, or, in its initial effect, alcoholic liquor.

Stimulate: Definition

1. Physiology, Medicine/Medical. to excite (a nerve, gland, etc.) to its functional activity.

Family: Aquifoliaceae

Specie

Active Chemical(s)

Plant Part

Amount

Referrence

Resources

Ilex paraguariensis ST. HIL.

Caffeine

Leaf

2,000- 20,000 ppm

[9] Duke.

Referrences for Aquifoliaceae Family

[9] : States: [Ilex paraguariensis (Aquifoliaceae)] "CAFFEINE Leaf 2,000 - 20,000 ppm: (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

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Family: Rubiaceae

Specie

Active Chemical(s)

Plant Part

Amount

Referrence

Resources

Coffea arabica

Caffeine

Seed

600-32,000 ppm

[1] Duke.

Genipa americana L.

Caffeine

Seed

22,500 ppm

[8] Duke.

Referrences for Rubiaceae Family

[1] : States: [Coffea arabica (Rubiaceae)] "CAFFEINE Seed 600 - 32,000 ppm: (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

[8] : States: [Genipa americana (Rubiaceae)] "CAFFEINE Seed 22,500 ppm; (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

[] : States: [ (Rubiaceae)] ""

[] : States: [ (Rubiaceae)] ""

Family: Sapindaceae

Specie

Active Chemical(s)

Plant Part

Amount

Referrence

Resources

Paullinia cupana KUNTH ex H.B.K.

Caffeine

Theobromine

Theophylline

Seed

Seed

Seed

25,000-76,000 ppm

330 ppm

570 ppm

[3] Duke.

[4] Duke.

[5] Duke.

Paullinia yoko SCHULTES & KILLIP

Caffeine

Bark

Leaf

27,300 ppm

Not stated

[6] Duke.

Referrences for Sapindaceae Family

[3] : States: [aullinia cupana (Sapindaceae)] "CAFFEINE Seed 25,000 - 76,000 ppm: (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

[4] : States: [Paullinia cupana (Sapindaceae)] "THEOBROMINE Seed 330 ppm; Anorexic; Antiasthmatic 10 mg/kg/orl/man; Anticellulitic; Arteriodilator; Bronchodilator; cAMP-Inhibitor IC50=0.06 mg/ml; cAMP-Phosphodiesterase-Inhibitor; Cardiotonic; cGMP-Phosphodiesterase-Inhibitor; CNS-Stimulant; Diuretic 300-600 mg/man/day; Emetic; Fetotoxic 100 mg/kg; Herbicide IC41=100 ppm; Myocardiotonic; Myorelaxant; Myostimulant; Pesticide; Stimulant; Teratogenic 100 mg/kg; Vasodilator"

[5] : States: [Paullinia cupana (Sapindaceae)] "THEOPHYLLINE Seed 570 ppm; (+)-Inotropic; Allergenic; Antiapneic; Antiasthmatic 5 mg/kg/orl/man; Antibradyarrhythmic; Antibronchitic; Anticellulitic; Antidote Charcoal & Propanolol; Antiemphysemic; Antineuralgic; Antirhinitic; Antispasmodic 100 uM; Antiviral; Arteriodilator; Bronchodilator; cAMP-Inhibitor IC50=0.06 mg/ml; cAMP-Phosphodiesterase-Inhibitor; Cardiovascular 30 mg/kg orl rat; cGMP-Inhibitor; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant; Diuretic 15 mg/kg ivn rbt; Fetotoxic 100 mg/kg; Herbicide IC58=100 ppm; Hypertensive; Hyperuricemic; Hypoglycemic; Myocardiotonic; Myorelaxant 100 uM; Pesticide; Prostaglandin-Secretor 10 mg/kg orl rat; Stimulant; Tachycardic; Teratogenic; Vasodilator"

[6] : States: [Paullinia yoko (Sapindaceae)] "(+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

Family: Sterculiaceae

Specie

Active Chemical(s)

Plant Part

Amount

Referrence

Resources

Cola acuminata (P. BEAUV.) SCHOTT & ENDL.

Caffeine

Seed

10,000-25,000 ppm

[7] Duke.

Theobroma cacao

Caffeine

Petiole

Seed

Testa

51-525 ppm

500-12,900 ppm

130-723 ppm

[10] Duke.

Referrences for Sterculiaceae Family

[7] : States: [Cola acuminata (Sterculiaceae)] "CAFFEINE Seed 10,000 - 25,000 ppm: (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

[10] : States: [Theobroma cacao (Sterculiaceae)] "CAFFEINE Petiole 51 - 525 ppm Seed 500 - 12,900 ppm Testa 130 - 723 ppm; (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

Family: Theaceae

Specie

Active Chemical(s)

Plant Part

Amount

Referrence

Resources

Camellia sinensis

Caffeine

Leaf

Shoot

3,810-93,000 ppm

38,100-47,900 ppm

[2] Duke.

[2] Duke.

Referrences for Theaceae Family

[2] : States: [ Camellia sinensis (Theaceae)] "CAFFEINE Leaf 3,810 - 93,000 ppm Shoot 38,100 - 47,900 ppm: (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

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Full referrence list

[1] : States: [Coffea arabica (Rubiaceae)] "CAFFEINE Seed 600 - 32,000 ppm: (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

[2] : States: [ Camellia sinensis (Theaceae)] "CAFFEINE Leaf 3,810 - 93,000 ppm Shoot 38,100 - 47,900 ppm: (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

[3] : States: [aullinia cupana (Sapindaceae)] "CAFFEINE Seed 25,000 - 76,000 ppm: (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

[4] : States: [Paullinia cupana (Sapindaceae)] "THEOBROMINE Seed 330 ppm; Anorexic; Antiasthmatic 10 mg/kg/orl/man; Anticellulitic; Arteriodilator; Bronchodilator; cAMP-Inhibitor IC50=0.06 mg/ml; cAMP-Phosphodiesterase-Inhibitor; Cardiotonic; cGMP-Phosphodiesterase-Inhibitor; CNS-Stimulant; Diuretic 300-600 mg/man/day; Emetic; Fetotoxic 100 mg/kg; Herbicide IC41=100 ppm; Myocardiotonic; Myorelaxant; Myostimulant; Pesticide; Stimulant; Teratogenic 100 mg/kg; Vasodilator"

[5] : States: [Paullinia cupana (Sapindaceae)] "THEOPHYLLINE Seed 570 ppm; (+)-Inotropic; Allergenic; Antiapneic; Antiasthmatic 5 mg/kg/orl/man; Antibradyarrhythmic; Antibronchitic; Anticellulitic; Antidote Charcoal & Propanolol; Antiemphysemic; Antineuralgic; Antirhinitic; Antispasmodic 100 uM; Antiviral; Arteriodilator; Bronchodilator; cAMP-Inhibitor IC50=0.06 mg/ml; cAMP-Phosphodiesterase-Inhibitor; Cardiovascular 30 mg/kg orl rat; cGMP-Inhibitor; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant; Diuretic 15 mg/kg ivn rbt; Fetotoxic 100 mg/kg; Herbicide IC58=100 ppm; Hypertensive; Hyperuricemic; Hypoglycemic; Myocardiotonic; Myorelaxant 100 uM; Pesticide; Prostaglandin-Secretor 10 mg/kg orl rat; Stimulant; Tachycardic; Teratogenic; Vasodilator"

[6] : States: [Paullinia yoko (Sapindaceae)] "(+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

[7] : States: [Cola acuminata (Sterculiaceae)] "CAFFEINE Seed 10,000 - 25,000 ppm: (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

[8] : States: [Genipa americana (Rubiaceae)] "CAFFEINE Seed 22,500 ppm; (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"

[9] : States: [Ilex paraguariensis (Aquifoliaceae)] "CAFFEINE Leaf 2,000 - 20,000 ppm: (+)-Inotropic; Adenosine-Antagonist; Analeptic 200 scu mus; Analgesic-Synergist; Antiapneic; Antiapoptotic; Antiasthmatic 5-10 mg/kg orl/man; Anticarcinogenic; Anticariogenic; Antidermatitic; Antiemetic; Antifeedant; Antiflu; Antiherpetic; Antihypotensive 250 mg/day/orl/man; Antinarcotic; Antiobesity; Antioxidant; Antirhinitic 140 mg/day/orl/man; Antiserotonergic 40 ipr rat 40 scu rat; Antitumor; Antitumor (Lung); Antivaccinia; Antiviral; Apoptotic; Arrhythmigenic 1,500 mg/man; cAMP-Phosphodiesterase-Inhibitor; Cancer-Preventive; Cardiotonic 10-25 orl dog 65-500 orl cat; Catabolic; cGMP-Phosphodiesterase-Inhibitor; Choleretic; CNS-Stimulant 100 orl mus 30 orl rat; Coronary-Dilator; Diuretic; Energizer 20-200 mg/man; Ergotamine-Enhancer; FLavor FEMA 125; Herbicide; Hypertensive; Hypoglycemic; Insecticide; Lypolytic; Myorelaxant; Neurotoxic; Pesticide; Phosphodiesterase-Inhibitor; Pyrogenic 13.3 mg/kg ipr rbt 15 mg/kg ipr cat 60 mg/day oral hmn; Respirastimulant; Spasmogenic 1,500 mg/man; Stimulant; Tachycardic; Teratogenic 14 orl rat; Topoisomerase-I-Inhibitor 0.1 nM 75 uM; Topoisomerase-II-Inhibitor 99 mM; Vasodilator"